Textbook of Human Disease in Dentistry
Mark Greenwood, Robin Seymour, John Meechan
Format: PDF / Kindle (mobi) / ePub
The Textbook of Human Disease in Dentistry is a comprehensive resource for all students of dentistry that provides uniquely integrated coverage of medicine, surgery, pharmacology, therapeutics, pathology and microbiology. It aims to provide its readers with the medical context of dentistry, to promote better understanding of how to provide effective dental treatment to patients affected by diseases and conditions. The Textbook of Human Disease in Dentistry is structured around the systems of the body and includes chapters on immunological disease, cardiovascular diseases, respiratory medicine, gastroenterology, dermatology, musculoskeletal disorders and neurological and special senses. A key aspect of the book is the relevance of particular diseases and/or their drug treatment to dentistry and in turn to patient dental management. Additional chapters are therefore provided on topics such as clinical examination and history taking, inflammation and anti–inflammatory drugs, infection control, pain and anxiety control, and care of the elderly. Filled with useful features and written in a lucid and accessible style, this book will provide its readers with a sound and accessible grounding in human diseases and their drug treatment and how they relate to dental care. Includes sections on all major diseases and conditions, describing aetiology, symptoms and treatment. Places dentistry in a medical context, providing guidance on examination and treatment protocols. Features information on drug treatment and planning dental care around it Illustrated with helpful clinical photographs, showing diseases and conditions.
Dr Mark Greenwood is a Consultant and Honorary Senior Lecturer in Oral and Maxillofacial Surgery in Newcastle upon Tyne. He is qualified in both dentistry and medicine and has fellowships in Dental Surgery, Oral and Maxillofacial Surgery and Surgery. A major interest is medical and dental education. He has written several publications in peer reviewed journals, mainly relating to medicine in dentistry and has published a book on the same subject. Professor Robin Seymour is at the School of Dental Sciences, University of Newcastle upon Tyne. He has published 8 books on topics related to human diseases, especially in the area of pharmacology. Likewise, Dr John Meechan has a similar profile. Other authors, Max Robinson , Iain Mcleod and Roger Jay provide input in the area of pathology, radiology and general medicine respectively.
It involves mainly the skull and clavicles. The head is large and brachycephalic with a persistent frontal suture. The clavicles are absent or stunted, conferring the ability to approximate the shoulders anteriorly. There is a persistent deciduous dentition, often unerupted permanent teeth, dentigerous cysts and supernumeraries. In cases of polyostotic fibrous dysplasia associated with pigmentation and precocious puberty in females, the name Albright’s syndrome is applied. Radiographically the
in a closed system there may be pockets of air trapped in the material being sterilised. This will become more or less saturated with water vapour depending on a variety of conditions in the immediate vicinity, such as the porosity of the material, the overall amount of air and water present and the volume of the container. It is, therefore, imperative that these and other factors are taken into account if sterility has to be guaranteed. Dry heat sterilisation is used to sterilise solid material
differences, a degree of specificity of antibiotics against bacterial ribosomes is achieved. Protein synthesis can be divided into a number of steps. Some of these stages are susceptible to antibiotic action. These steps are: ■ ■ ■ ■ ■ ■ ■ mRNA attaches to 30S subunit of ribosome tRNA brings amino acid to A site on ribosome Transpeptidation of amino acid to growing peptide from P site Ejection of tRNA from P site Translocation of tRNA from A to P site with growing peptide Ribosome moves one
(such as dental extractions) in patients with reduced resistance. When prophylactic antibacterials are prescribed, the correct antibacterial must be chosen and must begin at a suitable time and last for the appropriate length of time. The most suitable antibiotic is a bactericidal agent to which the patient is not allergic. A broad-spectrum penicillin such as amoxicillin is usually the drug of choice. Therapy is prophylactic with the objective of obtaining suitable levels of drug in the blood
concurrent drug therapy and liver disease. Warfarin is absorbed by the gastrointestinal tract and is extensively protein bound (98%). The plasma half-life is 35–37 hours. The drug is metabolised in the liver, and metabolites are excreted in the urine and faeces. The normal induction dose of warfarin is 10 mg and thereafter the maintenance dose depends upon the patient’s international normalised ratio (INR; see below). Monitoring patients on oral anticoagulants The INR, which is based on a