Stem Cells: Scientific Facts and Fiction
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Recent advances in the fields of medicine and technology have led to the development of stem cell therapy. A stem cell is a cell that has the potential to develop into many different types of cell in the body. It has the ability to divide and copy itself and at least one other specialized type of cell.
Stem Cells was written to provide information about the development of stem cell therapy, which can be used in the fields of research and medicine. The main goal of the book is to provide readers with an overview of the scientific facts about stem cells and its promising effects on the human body, as well as on the creation of new drugs and medicines. The book also highlights the ongoing clinical research into stem cells and lists the therapies whose effectiveness is being investigated.
Many scientists argue that stem cell therapy will be of great help to patients and society if it is proven to be safe and effective.
* Explains in straightforward, non-specialist language the basic biology of stem cells and their applications in modern medicine and future therapy
* Includes extensive coverage of adult and embryonic stem cells both historically and in contemporary practice
* Richly illustrated to assist in understanding how research is done and the current hurdles to clinical practice
and investment of commercial companies and the relatively straightforward nature of the disease – with just one cell type affected – places macular degeneration high on the list of diseases potentially treatable with stem cells. What is the Preferred Stem Cell for Transplantation? The choice of a specific stem cell type as a treatment for a particular disease is predominantly determined by the type of disease itself. If the disease is acute and life-threatening, only “off the shelf’ cells
cancer) with cytostatic (chemo) therapy: Loss of blood cells, as well as their precursor cells and blood stem cells. Muscle diseases, like Duchenne muscular dystrophy: Progressive loss of skeletal muscle cells caused by a genetic defect in a protein called dystrophin, which is important for normal muscle cell contraction. Some causes of infertility: Too few healthy oocytes or sperm cells are produced. Just imagine stem cells differentiate to gametes (“sex” cells) like these sperm cells … They
combination with special drugs, or by transplantation of a healthy liver from a donor. Scientists from the University of Pennsylvania in Philadelphia (USA) have tried to cure this disease by means of gene therapy. This entailed introducing DNA coding for the missing enzyme into the liver cells which then allows the cell to produce the missing protein. The coding DNA was packed in special viruses (the vector), which were injected into the portal vein of the liver of the patients. Mice and monkeys
doctors, patients and their families on how to deal with information provided by private stem cell clinics. This includes assessment of whether the claims of the clinic are based on real scientific facts, what the clinical evidence is for the therapeutic claims, and whether the therapy is likely to be harmless or prone to cause serious side effects. The risk of serious side effects is the greatest concern, since there are documented examples of patients who were significantly less well after
cells, leukemic blast cells, in the blood, caused by uncontrolled cell division of malignant precursor cells in the bone marrow. Leukemic cells all carry one specific recognizable DNA mutation in their genome – the leukemia-initiating mutation – while other mutations may be added during progression of the disease. Investigating the properties of these leukemic cells surprisingly revealed that the majority of cells could no longer divide and only a small cell population was still capable of