BRS Microbiology and Immunology (Board Review Series)
Format: PDF / Kindle (mobi) / ePub
BRS Microbiology and Immunology is designed specifically for medical and graduate students for successful preparation for the United States Medical Licensing Examination (USMLE). This newest edition features a full-color design and illustrations throughout. The book is divided into 12 chapters and presents both a "bug" approach followed by an organ systems approach. It remains a succinct description of the most important microbiological and immunological concepts and critical details needed to understand important human infections and the immune system function and malfunction. End-of-chapter review tests feature updated USMLE-style questions with rationales and four USMLE comprehensive examinations (in 50 question blocks like Step 1) help test memorization and mastery of the subject.
A companion website offers the fully searchable text and an online question bank.
fasciitis). a. Streptolysin S is a beta-hemolysin. b. Streptolysin O is an immunogenic, beta-hemolysin. Antibody to Streptolysin O is a marker of recent mucosal infections and or rheumatic heart disease (ASO titer) which is culture negative. 3. M proteins a. Attach Strep. pyogenes to cytoplasmic membrane. b. Class I M proteins extend through the cell wall to the cell surface; class II M proteins are not exposed on the surface. c. Strains causing rheumatic heart disease have exposed class I M
falsely negative in serious infection; they are negative early in infection and may remain negative if the patient is promptly treated with antibiotics. 96 BRS Microbiology and Immunology t a b l e 4.2 Important Bacterial Zoonoses Disease/Type Organism and Features Reservoir/Transmission Anthrax/pulmonary Anthrax/cutaneous Bacillus anthracis Gram-positive, aerobic rod Brucellosis/systemic Brucella melitensis, B. abortus, B. suis, B. canis Gram-negative rod Campylobacter jejuni Gram
Listeriosis/GI/septicemia Listeria meningitis Pasteurellosis/animal bite Plague/bubonic Plague/pneumonic Psittacosis Q fever/pneumonia with our without hepatitis Bartonella henselae Gram-negative pericellular rod Erysipelothrix rhusiopathiae Gram-positive rod Escherichia coli O157 and others with a shigalike toxin Leptospira interrogans return Spirochete with hooked ends Listeria monocytogenes Gram-positive nonspore-forming rod; somewhat resistant to heat; grows in cold Pasteurella multocida
as above but to all not previously vaccinated; recommended for college freshmen not vaccinated Toxoids of tetanus and diphtheria (every 10 years) 23-serotypes of capsular polysaccharides for those over 65 years plus many other groups Cell-free filtrate of an attenuated strain of Bacillus anthracis which makes the protective antigen but not the lethal factor nor edema factor Live attenuated vaccines are generally contraindicated in immunocompromised or pregnant women. There are many special
and a head CT was normal. The most likely cause of his symptoms was (A) (B) (C) (D) Cytomegalovirus Herpes simplex virus Parvovirus Rubella virus 4. A 23-year-old medical student on the Caribbean island of Dominica presents at the Student Health Clinic complaining of an increasingly severe headache and back and bone pain. Yesterday she was nauseated and vomited several times during the night. She has a 39.5°C/103°F fever, which appeared suddenly, and a generalized rash that blanches under